ZNF446 Antikörper (C-Term)

Produktnummer ABIN2781046

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch ZNF446 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Meerschweinchen, Hund, Maus, Rind (Kuh), Pferd und Kaninchen.

Kurzübersicht für ZNF446 Antikörper (C-Term) (ABIN2781046)

Target: ZNF446 (Zinc Finger Protein 446 (ZNF446))

Reaktivität: Human, Ratte, Meerschweinchen, Hund, Maus, Rind (Kuh), Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZNF446 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ZNF446 Antikörper

Bindungsspezifität: C-Term

Sequenz: SYPCEECGCS FSWKSQLVIH RKSHTGQRRH FCSDCGRAFD WKSQLVIHRK

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 75%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ZNF446. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ZNF446

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 450 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ZNF446

Target: ZNF446 (Zinc Finger Protein 446 (ZNF446))

Andere Bezeichnung: ZNF446

Hintergrund: ZNF446 contains a KRAB and three C(2)H(2) zinc fingers. ZNF446 is a transcription repressor when fused to GAL4 DNA-binding domain and co-transfected with VP-16. Overexpression of ZNF446 in COS-7 cells inhibits the transcriptional activities of SRE and AP-1, suggesting that the ZNF446 protein may act as a transcriptional repressor in mitogen-activated protein kinase (MAPK) signaling pathway to mediate cellular functions.
Alias Symbols: ZSCAN30, ZKSCAN20
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, ZSCAN22, ZNF396, KRT40, ZNF496, PGBD1, LZTS2, ZNF397, ZSCAN16, ZKSCAN7, ZNF446, ZSCAN32, ZNF232, ZSCAN9, ZNF165, ZSCAN21, ZNF24, TRIM27, PIN1, DGCR6, ACTN2, FHL5, DGCR6L, SUFU, ZNF263,
Protein Size: 450

Molekulargewicht: 49 kDa

Gen-ID: 55663

NCBI Accession: NM_017908, NP_060378

UniProt: Q9NWS9